The 200 diseases of autoimmunity are increasing worldwide, now affecting between 8 and
13% of all people in North America and Western Europe, each of whom have one, if not
several, autoimmune health conditions. There are a basic set of strategies to consider that
reduce the likelihood that autoimmune misrecognition can become established or persist.
Among the most important strategies to reduce autoimmunity are:
• Eliminate wheat and grains—The gliadin protein of wheat and related prolamin
proteins in other grains trigger the first step in generating the autoimmune
response. Eliminating grains entirely removes the initial trigger. This is absolutely
essential and more powerful than any drug.
• Restore vitamin D to healthy levels—We aim for a 25-hydroxy vitamin D level of
60-70 ng/ml, typically achieved with 6000 units of gelcap vitamin D3
supplementation per day.
• Correct omega-3 fatty acid deficiency—Higher doses in the range of 3600 mg
EPA + DHA from fish oil—and from fish oil only—contribute to subduing
• Manage bowel flora—In addition to supplementation with a high-potency
probiotic, a long-term prebiotic resistant starch program is essential to reverse
the dysbiosis and increased intestinal permeability characteristic of autoimmunity.
• Identify other food sensitivities—Other sensitivities, e.g., dairy, eggs, nuts, soy,
may occasional contribute to inflammation and autoimmunity and may need to
Autoimmune inflammatory diseases are on the rise.
In particular, inflammatory bowel
diseases, type 1 diabetes, and multiple sclerosis are becoming increasingly common
(Shapira 2010). The increasing prevalence of autoimmune diseases suggests that
something in the human condition has changed. Some have proposed that an unidentified
virus infecting millions of humans worldwide is to blame. Others blame vaccines. Industrial
chemicals that provoke endocrine disruption and disrupt the immune system may be a
factor. Other modern phenomena, such as reduced breastfeeding or cigarette smoking,
may also play roles. And, of course, grains have a hand in triggering autoimmunity, a role
magnified with advice to make “healthy whole grains” the cornerstone of diet. In
Undoctored U, the recognition that many foods, especially grains, have undergone
changes—chemical mutagenesis (the purposeful induction of mutations), mating with wild
grasses, and genetic modification—means that the immunogenicity, or immune activating
potential, has been magnified.
The diseases of autoimmunity are a pharmaceutical industry’s dream come true: chronic
conditions that require years of treatment, often involving intravenous biological agents
costing thousands of dollars per dose. This market is booming, now bringing in $40 billion
per year and growing. Conventional medical treatments of autoimmune diseases ignore
issues of increased intestinal permeability, molecular mimicry, immunomodulation by
nutrients vitamin D and omega-3 fatty acids, the participation of bowel flora, and the other
phenomena that ignite and propagate autoimmunity, choosing only to focus on shutting
down the immune response with drugs. Responses to these drugs are typically
incomplete, include dangerous side-effects such as liver damage and infection, and can
even allow other autoimmune conditions to develop.
The Undoctored approach, on the other hand, can be pursued without such side-effects,
while providing a wide spectrum of health benefits outside of autoimmunity.